Differential Diagnoses Seborrheic dermatitis: Greasy, yellow scales vs. dry, crusty lesions in AD. Scabies: Predominantly in warm, moist areas. Allergic contact dermatitis. Mycosis fungoides (T-cell lymphoma). Tinea corporis. Treatment strategies Moisturization: Lukewarm baths, emollients (petrolatum, Aquaphor). Topical Steroids: Hydrocortisone (mild), triamcinolone/betamethasone (moderate). Immunomodulators: Tacrolimus, pimecrolimus for moderate-severe AD. Advanced & Systemic Therapies Biologics: Dupilumab, tralokinumab, lebrikizumab, nemolizumab. JAK Inhibitors: Ruxolitinib, upadacitinib, abrocitinib. Other Topical Agents: PDE-4 inhibitors (crisaborole, roflumilast), taparinof cream. Adjuncts: Probiotics, antihistamines, antibiotics, bleach baths. Non-Medical Management Clothing: Cotton preferred, avoid wool. Environmental Modifications: Cool temperatures, humidifier use. Avoidance: Triggering foods, excessive sweating.