• Understand the Pathophysiology and Clinical Implications of Sickle Cell Disease • Review the genetic basis and systemic manifestations of sickle cell disease. • Discuss the impact of sickle cell disease on pregnancy and maternal outcomes. • Analyze Preoperative Assessment and Risk Stratification • Identify key clinical and laboratory markers relevant to anesthetic planning. • Evaluate comorbidities including retroviral disease and gestational hypertension. • Explore Anesthetic Management Strategies • Compare regional versus general anesthesia approaches in obstetric patients with sickle cell disease. • Discuss airway management, oxygenation, and fluid balance considerations. • Manage Intraoperative and Postoperative Complications • Recognize and respond to failed spinal blocks and rescue strategies. • Review postoperative care including pain management, oxygen therapy, and thromboprophylaxis. • Apply Evidence-Based Practices for Sickle Cell Disease in Obstetrics • Implement transfusion protocols and perioperative optimization strategies. • Understand the role of incentive spirometry, hydration, and multimodal analgesia. • Reflect on Multidisciplinary Coordination and System-Level Challenges • Emphasize the importance of early team involvement in high-risk obstetric cases. • Identify system gaps and propose improvements in maternal care for patients with hemoglobinopathies. • Promote Patient-Centered and Safe Anesthetic Care • Tailor anesthetic plans to individual patient needs and disease severity. • Foster awareness of psychosocial support and long-term management in special populations.