Key treatment methods Factor replacement therapy: This is the standard treatment for haemophilia A and B. Concentrates of the missing clotting factor (VIII or IX) are infused into the bloodstream to replace what the body is missing. Prophylaxis: Regular infusions given to prevent bleeds. On-demand: Infusions given to stop a bleed that has already started or before a medical procedure like surgery or dental work. Gene therapy: This is a newer treatment that aims to give the body the genetic instructions to produce clotting factors itself. For haemophilia B: Hemgenix® was the first gene therapy approved by the FDA in 2022. For haemophilia A: Roctavian® was approved in 2023. Emicizumab: A bispecific monoclonal antibody for haemophilia A that can be injected subcutaneously (under the skin) and mimics the function of factor VIII. Supportive and preventative measures Medication management: Avoid medications with aspirin or NSAIDs (e.g., ibuprofen) which can worsen bleeding. Use safer options like paracetamol for pain. Exercise and physical therapy: A physical therapist can guide exercises to help with joint health and recovery from bleeds. Injury prevention: Take precautions to avoid injury, such as wearing protective gear like helmets and kneepads. Good dental hygiene: Prevent gum disease, which can lead to bleeding. Medical alert bracelet: This ensures medical personnel know you have haemophilia in an emergency.